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Welcome to the Stewart-Ornstein Laboratory
We aim to understand how DNA damage signaling is regulated by cell state. We use live cell imaging, sequencing, and computational model building to study DNA damage and repair at multiple timescales. Ultimately we aim to apply our results to improve cancer therapy.
Our lab environment is interdisciplinary, inclusive, and inventive. We have positions available for graduate students and postdocs. Contact me if you are interested in joining the lab.
Our current interests include:
  • Quiescence and DNA damage signaling
  • p53 DNA binding and regulation
  • Tissue specific DNA damage signaling
  • Optimizing cancer therapy
Our work is funded by generous support from the NIH and UPMC.